Health Info #4

Peripheral Stem Cell Collection:
The process of removing stem cells from the bloodstream is called apheresis. Most patients who have autologous transplants will have stem cells collected from their peripheral bloodstream. Also, allogeneic donors may donate stem cells from their peripheral bloodstream.

The Pheresis Process:
Stem cells collection in small children is performed on the inpatient unit after a central venous pheresis catheter has been placed. Stem cell collection in older children and adults will be performed in the Blood Bank. The pheresis process takes about 4-6 hours. It may take more than one day of pheresis to collect enough stem cells for the transplant. Sterile tubing is connected from the pheresis catheter to the pheresis machine and back to the other side of the catheter. In larger donors without a catheter, the tubing will connect to an IV in each arm. The donor's blood will pass through the pheresis machine, which will separate and collect the stem cells and return the other blood cells to the donor. Allegeneic stem cells will usually be processed and infused the same day as the collection. Temporary side affects of apheresis include low calcium. low potassium, low platelet count and low red blood cell count. Transfusions and electrolyte infusions may be used to prevent or manage these side affects if they occur.